Monday, February 14, 2011

Dog Arthritis Treatment Options Part 4 – Deramaxx 

Deramaxx, generic name Deracoxib, was first developed by Novartis. It is a prescription drug that comes in the form of an artificially flavored tablet. Deramaxx is a COXIB class NSAID.  This means that Deramaxx is able to selectively suppress only the effects of the pro-inflammatory COX-2 enzyme while allowing sparing COX-1 enzyme, which is involved in the protective lining of the stomach and intestines and also needed for proper blood circulation through the kidneys.

Talking to Your Vet about Deramaxx 

 When considering the use of Deramaxx, it is important to have a thorough discussion about the dangers of the drug. The following are some of the questions you need to ask your vet. 
  • What are the side effects of Deramaxx?  Deramaxx can cause gastro-intestinal damage and renal failure in dogs. Dog owners should be monitoring for bloody, black, or tarry stools; bloody vomit; unexplained weight gain; lethargy; skin rashes or constant itching; jaundice; or unusual bruising or bleeding.  If your dog develops any of these side effects, take them to the nearest animal hospital or clinic and have your dog examined by a vet so the right treatment can be given.
  • Is Deramaxx safe to use with other drugs? Your vet should inform you of the drugs that are known to have harmful reactions when taken alongside Deramaxx. Some of these drugs are other NSAIDs, steroids, methotrexate, diuretics, Phenobarbital, and antibiotics.
  • Is it safe for all dogs? Unfortunately, the answer is no. Deramaxx is not safe for dogs that are allergic to NSAIDs or those with pre-existing stomach, intestine, or liver conditions. As a precaution, Deramaxx should not be given to pregnant or lactating dogs.
 The Use of Deramaxx

It is always important to follow your vet’s instructions, especially when it comes to administering the right dosage.  

For Deramaxx, 0.45 to 0.91 milligrams per pound of the dog’s weight once a day is normally recommended for the management of dog arthritis pain and inflammation. The drug is also helpful in the suppressing of post-operative pain. Here, the dosage is usually 1.4-1.8 milligrams once a day for a maximum of seven days 
Deramaxx can be administered with or without food. Just make sure your dog has enough water to drink.  

For proper storage, the drug should be kept in room temperature and protected from direct sunlight.

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